Innate and adaptive immune traits are differentially affected by genetic and environmental factors
نویسندگان
چکیده
منابع مشابه
Innate and adaptive immune traits are differentially affected by genetic and environmental factors
The diversity and activity of leukocytes is controlled by genetic and environmental influences to maintain balanced immune responses. However, the relative contribution of environmental compared with genetic factors that affect variations in immune traits is unknown. Here we analyse 23,394 immune phenotypes in 497 adult female twins. 76% of these traits show a predominantly heritable influence,...
متن کاملKiller Cell Immunoglobulin-Like Receptors Influence the Innate and Adaptive Immune Responses
Natural killer (NK) cells are a subset of lymphocytes which play a crucial role in early innate immune response against infection and tumor transformation. Furthermore, they secrete interferon-γ (IFN-γ) and tumor necrosis factor (TNF) prompting adaptive immu-nity. NK cells distinguish the unhealthy cells from the healthy ones through an array of cell-surface receptors. Human NK cells use inhibi...
متن کاملIsabgol (Plantago ovata Forsk) seed germination and emergence as affected by environmental factors and planting depth
Isabgol (Plantago ovata Forsk) seed germination and emergence in response todrought (Polyethylene glycol 8000) and salinity stress (NaCl), temperature, pH andplanting depth were studied in laboratory and greenhouse experiments. Base,optimum and ceiling germination temperature were estimated as 3.35, 21.24 and35.04 oC, respectively. Isabgol seed is rather tolerant to low water potential and high...
متن کاملDifferential Effects of Environmental and Genetic Factors on T and B Cell Immune Traits
Effective immunity requires a complex network of cellular and humoral components that interact with each other and are influenced by different environmental and host factors. We used a systems biology approach to comprehensively assess the impact of environmental and genetic factors on immune cell populations in peripheral blood, including associations with immunoglobulin concentrations, from ∼...
متن کاملRanking of factors which affect and are affected by employees' psychological empowerment using QFD approach
the present research aims to investigate and rank which affect and re affected by employees’ psychological empowerment in order to help organizations and their employees to be more committed to their jobs by accessing resources and feeling control and ownership and use initiative in their works in order to do works well so that their effectiveness and efficiency within organization will be impr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Communications
سال: 2017
ISSN: 2041-1723
DOI: 10.1038/ncomms13850